Authors
François Briand, Estelle Grasset, Nicole Endlich, VedranDrenić, Blazej Dolicki, Thomas de Bel, Thierry Sulpice
Abstract
Our aim was to validate and optimize a rat model of IgA nephropathy for drug efficacy studies using quantitative image analysis of kidney. To demonstrate the accuracy of our imaging methods, we evaluated atrasentan, a selective Endothelin A receptor Antagonist currently evaluated in phase III clinical trials.
